Bengaluru Scientists Build Low-Cost Device to Detect Sickle Cell Anemia — A Major Leap for India’s 2047 Health Mission
Bengaluru – In a major scientific breakthrough, researchers at the Raman Research Institute (RRI) have developed an affordable and portable device that can detect sickle cell anemia (SCD), blood infections, and even tumour cells — making it a potential game-changer in India’s fight against anemia.
Led by Professor Gautam Soni, the RRI team designed the Electro-Fluidic Device, which measures the stiffness and volume of red blood cells (RBCs) to detect abnormalities. The device uses advanced techniques like free-flight and constricted-flight modes to differentiate between healthy and sickle-shaped RBCs.
What is Sickle Cell Disease?
Sickle cell anemia is a genetic blood disorder where red blood cells become rigid and sickle-shaped, disrupting blood flow and oxygen transport in the body. These cells often block small blood vessels, leading to severe pain, organ damage, and anemia. India, particularly rural and tribal regions, records a high prevalence of SCD.
Why This Device is Revolutionary
Currently, high-performance liquid chromatography (HPLC) is the standard test for detecting SCD — but it is expensive and not scalable for rural health centers.
RRI’s new invention offers:
✅ Low-cost operation
✅ Portable screening
✅ High resolution & throughput
✅ Advanced detection of blood cell stiffness
“This device studies changes in red blood cells with high resolution, making it ideal for detecting SCD and possibly even cancer cells,” said lead scientist Prof. Gautam Soni.
📊 India’s Anemia Crisis: The Need for Innovation
According to the National Family Health Survey (2019–21):
57% of Indian women (15–49 years) suffer from anemia
67% of children (6–59 months) are anemic
52% of pregnant women also face the condition
This innovation supports the Government of India’s mission to eliminate sickle cell disease by 2047, especially in underserved regions.
Beyond SCD: Tumor & Animal Disease Detection Possible
RRI says this versatile device could be used for detecting tumor cells in the blood and for veterinary disease detection, offering a scalable solution for both human and animal healthcare.
Made in India, Designed for Impact
The device, developed by Soni, S. Kaushik, and A. Mishra, has the potential to reach millions of people in rural India, offering early detection and timely treatment — aligning perfectly with India’s push for tech-led public health transformation.
