Johannesburg, South Africa – November 23, 2025
The G20 leaders and global partners pledged $11.34 billion at the Global Fund’s eighth replenishment summit, the first held on African soil. Hosted by South Africa and the United Kingdom, the summit saw commitments aimed at combating HIV/AIDS, tuberculosis, and malaria over the next three years.
The pledged amount, though short of the $18 billion target, represents a critical investment in global health, with significant focus on Africa, where the burden of these diseases remains highest. Donors including the United States, which pledged $4.6 billion, South Africa, the UK, Germany, and the Gates Foundation reaffirmed their support. Several African nations also participated, highlighting their growing role in health system financing.
South African President Cyril Ramaphosa emphasized Africa’s leadership in driving health innovation and resilience. The summit encouraged private sector involvement and stressed a country-driven approach to health partnerships. Despite funding constraints, the Global Fund’s model remains a beacon of solidarity and transformation in global health.
This collective effort aims to enhance prevention, treatment, and care, accelerating progress towards universal health coverage and stronger health systems worldwide.














